# Smallpox Smallpox represents a key moment in Magic's design philosophy around symmetrical effects. This uncommon from Duel Decks: Nissa vs. Ob Nixilis appeals to players who appreciate efficient, balanced removal that demands thoughtful sequencing. The card's appeal lies in its versatility—it can target creatures, lands, or hand disruption simultaneously, making it valuable in limited formats and casual play. Collectors often view Smallpox through the lens of its original printings, which carry more cachet than this Duel Decks version. The nonfoil uncommon here is straightforward and accessible, lacking the premium treatment that might elevate it for set completionists. It's a solid utility card rather than a chase piece.